CLINICAL GUIDE

Management of Care

Nutritional support, therapies, and strategies for living with Short Bowel Syndrome

Short Bowel Syndrome care is highly individualized. Successful management usually focuses on three goals: correct nutritional deficiencies, stabilize fluid balance, and promote intestinal adaptation—always guided by your specialized care team.

CARE GOALS
Three pillars of SBS management
1️⃣
Correct deficiencies
Restore nutrients the remaining bowel cannot absorb well enough on its own
2️⃣
Stabilize fluids
Protect hydration and electrolytes day to day
3️⃣
Promote adaptation
Help the remaining intestine work as effectively as possible over time

01 · NUTRITION
Nutritional support
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IV NUTRITION

Parenteral Nutrition (PN / TPN)

Intravenous nutrition through a central line when the remaining bowel cannot absorb enough from food alone.

🍽️
GUT STIMULATION

Enteral nutrition & oral intake

Tube feeding or oral intake can stimulate the remaining gut and support intestinal adaptation over time.

02 · DIET
Dietary strategies
🕐

Small, frequent meals

Often 6–8 smaller meals per day to reduce dumping, slow transit, and help control diarrhea—follow your dietitian’s plan.

🥗

Nutrient-dense choices

Emphasis is often on lean proteins, complex carbs, and appropriate fats, while limiting simple sugars that can worsen diarrhea.

03 · FLUIDS
Fluid & electrolyte balance
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Oral rehydration solutions (ORS)

Solutions with balanced salt/sugar ratios often work better than plain water or typical sports drinks for SBS-related fluid loss.

🧪

Lab monitoring

Regular bloodwork helps track sodium, potassium, magnesium, and other values to prevent serious complications.

Laboratory & Imaging →

04 · MEDICATIONS
Common therapy categories
⏱️

Anti-diarrheals

May slow transit so remaining bowel has more time to absorb.

🔬

Bile acid sequestrants

May help when the ileum is missing and bile salts irritate the colon.

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GATTEX® (teduglutide)

A GLP-2 analog that may support adaptation and help reduce PN dependence in selected patients.

Learn about GATTEX® →

05 · SURGERY
Surgical options
✂️

STEP / LIFT procedures

Bowel-lengthening approaches that may slow transit and improve absorption in selected patients.

🏥

Intestinal transplant

Considered for irreversible intestinal failure with life-threatening PN complications—evaluated at specialized centers.

Transplants →

YOUR TEAM
Who helps manage SBS care
GI

Gastroenterologist

Motility, labs, oversight

SX

GI surgeon

Lengthening & transplant evaluation

RD

Specialized dietitian

PN formulas & meal planning

🧠

Emotional support matters

Living with SBS and intensive nutrition therapies carries a real emotional toll. Peer support and counseling help patients and families navigate the journey.

Mental Health & SBS →

CONTINUE LEARNING
Related resources
Medical disclaimer
This content is for educational purposes only. Always consult your gastroenterologist or specialized care team before making changes to treatment, diet, or therapy.