Original Article published by: www.news-medical.net
The research team conducted the study in zebrafish, using a validated SBS model created in the Grikscheit laboratory. This model allowed the investigators to study matched samples of small intestine from zebrafish who had bowel surgery and those who underwent “sham” or control surgery. According to first author, Kathy A. Schall, MD, “Most studies of SBS focus on the epithelial cells that line the intestine but this model allowed us to focus on systemic effects and the associated genetic alterations responsible for those effects.”